What is Alpha Lipoic Acid?

Alpha Lipoic Acid is a vitamin-like compound with powerful anti-oxidant properties. Because it dissolves in both water and fat, Alpha Lipoic Acid has been called “the universal antioxidant.”

What is an anti-oxidant and why are they important?

Anti-oxidants like Alpha Lipoic Acid, Vitamin C, and Vitamin E capture unstable oxygen molecules in the body and prevent them from damaging healthy cells in the body. Unstable oxygen molecules are also referred to as free radicals.

How does Alpha Lipoic Acid slow down the aging process?

By capturing and flushing out free radicals that can harm healthy tissue. The process of oxidation is literally the same process that causes metals to rust. Think of Alpha Lipoic Acid as a rust remover for your body!

Can I get sufficient Alpha Lipoic Acid by eating the right foods?

Yes, but most of us won’t. The diet of the typical American does not include sufficient vegetables or the right kinds of food to provide sufficient amounts of Alpha Lipoic Acid.

Has there been sufficient research on Alpha Lipoic Acid?

A meta-search on PubMed, the web site of the National Library of Medicine, showed over 1300 studies involving Alpha Lipoic Acid. These studies include both animal and human research and double-blind, placebo controlled clinical trials.

I don’t have diabetes and I am in overall good health. Do I still need to take Alpha Lipoic Acid supplements?

Alpha Lipoic Acid assists the B vitamins in producing energy from the proteins, carbohydrates, and fats consumed through foods. Healthy people who take ALA report feeling better and more energetic.

Alpha lipoic acid is the active ingredients in PhenQ

Is it safe?

Clinical studies and years of use by people in Germany, Italy and other European countries verifies that Alpha-lipoic acid is very safe at commonly recommended dosages, although occasionally it causes mild stomach upset and in rare cases it can trigger an allergic skin rash. If you experience any of these reactions, reduce the dose or stop taking the supplement.

Alpha Lipoic Acid Clinical Studies

A meta-search on PubMed, the web site of the National Library of Medicine, showed over 1300 studies involving Alpha Lipoic Acid. These studies include both animal and human research and double-blind, placebo controlled clinical trials.

Here are some of the major clinical studies done on Alpha Lipoic Acid. In addition, abstracts of Alpha Lipoic Acid Research from the MEDLINE can be read here: Alpha Lipoic Acid Research

Bailey, D. M. and B. Davies (2001). “Acute mountain sickness; prophylactic benefits of antioxidant vitamin supplementation at high altitude.” High Alt Med Biol 2(1): 21-9.

Dietrich, M., G. Block, M. Hudes, J. D. Morrow, E. P. Norkus, M. G. Traber, C. E. Cross and L.

Grieb G, [Alpha-lipoic acid inhibits HIV replication]. Med Monatsschr Pharm 1992 Aug;15(8):243-4. (Article in German).

Jacob S Streeper RS Fogt DL Hokama JY Tritschler HJ Dietze GJ Henriksen EJ, The antioxidant alpha-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle. Diabetes. 1996 Aug; 45(8): 1024-9 1996 0012-1797

Merin JP Matsuyama M Kira T Baba M Okamoto T, Alpha-lipoic acid blocks HIV-1 LTR-dependent expression of hygromycin resistance in THP-1 stable transformants. FEBS-Lett. 1996 Sep 23; 394(1): 9-13 1996 0014-5793.

Murray, Michael, ND, Pizzorno, Joseph, ND. Encyclopedia of Natural Medicine, second ed. Prima Publishing, Rocklin. 1998.

Packer (2002). “Antioxidant supplementation decreases lipid peroxidation biomarker F(2)- isoprostanes in plasma of smokers.” Cancer Epidemiol Biomarkers Prev 11(1): 7-13.

Packer L Tritschler HJ Wessel K, Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free-Radic-Biol-Med. 1997; 22(1-2): 359-78 1997 0891-5849.

Alpha Lipoic Acid and Hidden Benefits

Patrick, L. (2000). “Nutrients and HIV: part three – N-acetylcysteine, alpha-lipoic acid, L- glutamine, and L-carnitine.” Altern Med Rev 5(4): 290-305.

Reljanovic, M., G. Reichel, K. Rett, M. Lobisch, K. Schuette, W. Moller, H. J. Tritschler and H. Mehnert (1999). “Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy.” Free Radic Res 31(3): 171-9.

Roesler, R., J. Quevedo, R. Walz and M. Bianchin (1999). “A randomized, double-blind, placebo-controlled trial of deprenyl and thiotic acid in HIV-associated cognitive impairment.” Neurology 52(9): 1920-1.

Ruhnau, K. J., H. P. Meissner, J. R. Finn, M. Reljanovic, M. Lobisch, K. Schutte, D. Nehrdich, H. J. Tritschler, H. Mehnert and D. Ziegler (1999). “Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy.” Diabet Med 16(12): 1040-3.

Sachse, G. and B. Willms (1980). “Efficacy of thioctic acid in the therapy of peripheral diabetic neuropathy.” Horm Metab Res Suppl 9: 105-7.

Strokov, I. A., N. A. Kozlova, V. Mozolevskii Iu, S. P. Miasoedov and N. N. Iakhno (1999). “[The efficacy of the intravenous administration of the trometamol salt of thioctic (alpha-lipoic) acid in diabetic neuropathy].” Zh Nevrol Psikhiatr Im S S Korsakova 99(6): 18-22.

PhenQ UK Reviews – Slimming Pill

Ziegler, D. and F. A. Gries (1997). “Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy.” Diabetes 46 Suppl 2: S62-6.

Ziegler, D., M. Hanefeld, K. J. Ruhnau, H. P. Meissner, M. Lobisch, K. Schutte and F. A. Gries (1995). “Treatment of symptomatic diabetic peripheral neuropathy with the anti- oxidant alpha-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study).” Diabetologia 38(12): 1425-33.

Ziegler, D., H. Schatz, F. Conrad, F. A. Gries, H. Ulrich and G. Reichel (1997). “Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie.” Diabetes Care 20(3): 369-73.